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Native chemical ligation (NCL) and bis (2-sulfanylethyl) amido (SEA) ligation (theory only)

Scientific and technical environment of the training course

Mécanismes de la tumorigenèse et thérapies ciblées - Equipe CBC - UMR 8161

COURSE DIRECTOR

Oleg MELNYK

Senior researcher

UMR 8161

LOCATION

LILLE (59)

ORGANISATION

1 day
From 4 to 9 attendees
Training course in English

TRAINING FEES

600 Euros

AT THE END OF THE TRAINING COURSE

Satisfaction survey from trainees
A certificate of attendance is delivered.

COURSE DATE

17294 : Consult us

January February March April
May June July August
Sept. Oct. Nov. Dec.

OBJECTIVE

- Master at a theoretical level the NCL and SEA ligations and the desulfurization reactions

AUDIENCE

Technicians, engineers, researchers

PRE-REQUIREMENT

Master the basic notions of synthetic organic chemistry (bachelor's degree). Master the theory and practice of the solid phase peptide synthesis (see for example the internship n° 17174 within this catalogue)

TRAINING PROGRAMME

Theory
- Native chemical ligation (NCL)
- SEA ligation
- SeEA ligation (selenium version of SEA ligation)
- Application of NCL and SEA ligation, including the latent properties of the SEA group, to the total synthesis of proteins, cyclic peptides, branched peptides and cyclic and branched peptides.
- Desulfurization/deselenization reactions

This course can be followed by a 3 day - pratical part (Ref. 17293 within this catalogue).

SPEAKER

O. Melnyk (researcher)

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